Cochleates Derived from Vibrio cholerae O1 Proteoliposomes: The Impact of Structure Transformation on Mucosal Immunisation
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Cochleates Derived from Vibrio cholerae O1 Proteoliposomes: The Impact of Structure Transformation on Mucosal Immunisation
Cochleates are phospholipid-calcium precipitates derived from the interaction of anionic lipid vesicles with divalent cations. Proteoliposomes from bacteria may also be used as a source of negatively charged components, to induce calcium-cochleate formation. In this study, proteoliposomes from V. cholerae O1 (PLc) (sized 160.7±1.6 nm) were transformed into larger (16.3±4.6 µm) cochleate-like st...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0046461